4 Catalyzer is a startup accelerator dedicated to maximizing societal impact

We envision, incorporate, finance, support, and mentor a select number of startups that we are committed to make successful. Each startup is funded from the beginning for success, allowing the team to exploit new developments in physics, math, and the life sciences to create truly novel technologies and do the science enabled by being first.

Our Startups have decoded the Neanderthal Genome, enabled what the New England Journal calls the new age of molecular medicine, helped crack the disappearance of the honey bee, sequenced the first personal genome, developed promising new drugs for breast cancer, been named three times as World Economic Forum Technology pioneers, and twice as Science Magazines top innovations of the year.

The startups have dedicated space and we work intimately with them to support them strategically, administratively, legally, commercially, with regulatory agencies, as well as offer them core design, engineering, software platforms, and a supplier and manufacturing network to accelerate their programs.

Changing the lives of those we love

At 4Catalyzer we strive to transform 21st century medicine by solving today’s most challenging problems – across life science research tools, medical devices and therapeutics. We aspire to create significant societal impact and are motivated by the idea that our products will change the lives of people we love.

Fundamentally, we are focused on developing new types of sensors and pairing them with deep learning to get a window into biology and medicine that nobody has ever had before. We have audacious plans – but we have an unbeatable team and a founder that has disrupted biomedical science successfully more than once.

Come build the next $100 billion dollar industry with us and change the world.


Jonathan Rothberg

Chairman and Founder of all 4C companies
Founder Ion Torrent, RainDance, 454 Life Sciences, ClariFi, CuraGen

Darius Shahida

Chief Business and Chief Strategy Officer
Head of Trading at a Birch Grove Capital, Cross Asset Special Situations Desk at Morgan Stanley



Chair of Department of Neurosurgery

Elazer R. Edelman

MIT & Harvard
Professor in Medical Engineering and Science at MIT, Professor of Medicine at Harvard Medical School

Chris Mason

Professor of Physiology and Biophysics

Michael Mina, MD, PhD

Chief Medical Officer

Brian Litt

Professor of Neurology and Bioengineering

Antoine van Oijen

U. Groningen
Professor & Chair of Advanced Materials

Pierre Khuri-Yakub

Professor of Electrical Engineering

Max Tegmark

Professor of Physics

David Ferrucci

Inventor of IBM's Watson Supercomputer

Lindsey Rhodes

UAB Department of Ophthalmology and Visual Sciences
Director of Teleophthalmology

Jeff Huber

Founding CEO of GRAIL | Co-Founder & General Partner at Triatomic Capital | Former Google

Khan Siddiqui


David Rosenthal

Chair of 4C Medical Advisory Board

Chip Truwit

Senior Medical Director

Eddie Knopp

Senior Medical Director

I-Zu Huang

identifeye HEALTH
Head of Clinical Development and Medical Affairs

Jill Kalman

Northwell Health
SVP, Chief Medical Officer and Deputy Physician-in-Chief

John Martin

Chief Medical Officer

Kahlil Salman

Director, Clinical Informatics

Mike McConnell

identifeye HEALTH
Chief Medical Officer